New systemic therapies are urgently needed for triple-negative breast cancer tumors because hormonal therapies and HER2-targeted agents are ineffective. Nature Reviews Clinical Oncology
Studies suggest that an elevated concentration of adenosine-triphosphate (ATP) in malignant B-cell lymphocytes from CLL impair the p53 gene to induce apoptosis of cells. Laboratory Medicine
In this Expert Interview from SABCS 2007, Dr. William J. Gradishar details the latest novel drug combinations that may benefit patients with advanced breast cancer. Medscape Hematology-Oncology
When possible, metastatic lesions should be biopsied in breast cancer patients because the biology of cancer is likely to change and can affect treatment. Medscape Medical News
Lentiviral vectors successfully integrate β-globin gene into hematopoietic stem cells, with vector-bearing cells in whole blood now topping 10%. Medscape Medical News