Although progressive multifocal leukoencephalopathy (PML) rarely accompanies rheumatic diseases, when it does, it seems to occur most often with systemic lupus erythematosus (SLE), researchers report in the December issue of Arthritis and Rheumatism. Reuters Health Information
In a cohort study, a high body mass index was associated with a less severe disease outcome in patients with rheumatoid arthritis who test positive for anticyclic citrullinated peptide antibodies. Medscape Medical News
Few studies have investigated the basis for the difference in clinical response to TNF-alpha blockade therapy. Can pre-treatment synovial TNF-alpha or IL-1 expression predict TNF blockade response? Rheumatology