New research indicates that the null state (-46C/C genotype) of the Duffy Antigen Receptor for Chemokines (DARC), which is linked to malaria resistance, confers a survival advantage for HIV-infected African Americans with leukopenia. Reuters Health Information
Poor survival among HIV-infected African Americans undergoing renal replacement therapy (RRT) likely reflects undertreatment with highly active antiretroviral therapy (HAART), according to a report in the December 15th Clinical Infectious Diseases. Reuters Health Information
The LMB86 chemotherapy regimen is highly effective against AIDS-related Burkitt lymphoma with bone marrow and/or central nervous system involvement, according to a new study -- if patients have relatively high CD4 counts and good performance status. Reuters Health Information
Prolonged, untreated HIV-1 infection does not appear to impair semen quality, according to a report in the September issue of Fertility and Sterility. Reuters Health Information
Intra-partum nevirapine, given to prevent HIV transmission, contributes to HIV resistance mutations to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) - but a one-month postpartum course of zidovudine plus didanosine helps avoid this problem. Reuters Health Information
