Two of the largest trials ever conducted in chronic lymphocytic leukemia show that the addition of rituximab to chemotherapy significantly improves progression-free survival. Medscape Medical News
Captured circulating tumor cells present a relatively noninvasive source of tumor material for assessing biomarkers, and provide "real-time" information about the disease. Medscape Medical News
Estrogens behave as protective agents on the development of colorectal cancer, and hormonal-replacement therapy is associated with an increased survival rate in women with this disease. Expert Review of Endocrinology and Metabolism
For the first time, a significant prolongation of survival has been seen in this disorder, leading to calls for azacitidine to be offered to all high-risk patients. Medscape Medical News
Acute myeloid leukemia is a challenging disease to treat, but new molecular and cytogenetic markers can help clinicians guide patients to more effective and safe therapy. The current article reviews these markers and offers strategies for their clinical application. Journal of the National Comprehensive Cancer Network
The FDA has approved safety labeling revisions for metronidazole injection, iron dextran injection (DexFerrum and INFeD), and nilotinib HCl monohydrate capsules (Tasigna). Medscape Medical News